ACE-031
1 mg × 10 vials
For laboratory procurement
- Catalog number
- AE1
- Listed specification
- 1 mg
- Vials per pack
- 10 vials
- Test reports
- No report published for this SKU
- Current supply lot
- Lot documents with your quote
Compound profile
ACE-031 is a soluble fusion protein combining the extracellular region of ActRIIB with a human IgG1 component.
Identity
- Molecular formula
- Not recorded
- Average molecular weight
- Not recorded
- CAS number
- Not recorded
The opened records describe the fusion design but do not verify its complete sequence, glycoform, formula, average molecular weight, CAS, PubChem compound record or construct-specific UniProt accession. SMILES and a small-molecule structure do not apply. No protein diagram is generated.
Identity data from: PubMed PMID 41686840
Research overview
ACE-031 is described in the cited animal study as a protein containing the extracellular region of activin receptor type IIB, abbreviated ActRIIB, fused to human IgG1 [2]. This soluble construct is distinct from the complete receptor in a cell membrane. A review of activins and inhibins provides the broader context for the ligands, receptor complexes and intracellular signaling associated with this protein family. The fusion name identifies a construct design, rather than a complete amino-acid sequence or a specified glycoform [1].
The ACE-031 study used common marmosets, Callithrix jacchus, as its animal model and compared groups assigned to the fusion protein or a vehicle control. Investigators collected repeated observations during the experiment and performed tissue-based measurements at its end. This is an animal-model investigation of the soluble ActRIIB construct, not a structural determination of every molecular form in a laboratory preparation. The opened record supports the reported fusion identity and the model description, while leaving a complete construct sequence and detailed molecular composition unverified. Accordingly, a single chemical formula or a residue diagram would imply a degree of structural specification not supplied by these sources [2].
Laboratory storage and handling
Keep the sealed vial cold, dry and protected from light, following the conditions in the documentation supplied with the lot. Let the vial reach room temperature before opening to limit moisture condensation. Avoid repeated freezing and thawing of laboratory stocks. Record the lot identifier and the material form with each experiment, and use standard laboratory protective equipment.
Questions about ACE-031
Is ACE-031 an intact cell-surface receptor?
No. The cited study describes a soluble fusion of the extracellular ActRIIB region with human IgG1. That design differs from the complete receptor embedded in a cell membrane [2].
Why are the sequence and molecular weight absent?
The opened records do not verify the complete construct sequence or glycoform. Without that specification, a single formula and average molecular weight cannot be assigned here.
Which animal model is described in the cited study?
The study used common marmosets, Callithrix jacchus, with a vehicle-control comparison. Its observations belong to that animal experiment and do not define every preparation bearing the fusion name [2].
References
- Activins and Inhibins: Roles in Development, Physiology, and Disease. Cold Spring Harb Perspect Biol 2016. PMID 27328872
- ACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset (Callithrix jacchus). PLoS One 2026. PMID 41686840
Identity data checked on 2026-10-03. Literature summaries describe published research models and are not specifications of any product lot.
Compare specifications
1 catalog entryTest reports
Third-party testNo sample report is published for this item yet. Ask for the documents for the exact lot in your quote.
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Request current lot documentsB2B procurement
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